Tirzepatide dosage calculator
The whole 2.5 to 15 mg ladder, converted into the mark on your syringe. Works for 10, 20, 30 and 60 mg vials.
Dose to units, at the standard setup
| Dose | Draw | U-100 units | Doses per vial | Vial lasts |
|---|---|---|---|---|
| 2.5 mg | 0.25 mL | 25 units | 12 | 84 days |
| 5 mg | 0.5 mL | 50 units | 6 | 42 days |
| 7.5 mg | 0.75 mL | 75 units | 4 | 28 days |
| 10 mg | 1 mL | 100 units | 3 | 21 days |
| 12.5 mg | 1.25 mL | 125 units | 2 | 14 days |
| 15 mg | 1.5 mL | 150 units | 2 | 14 days |
Based on a 30 mg vial reconstituted with 3 mL of bacteriostatic water, which is 10 mg/mL, drawn on a standard U-100 insulin syringe.
About the numbers above
Tirzepatide is a dual GIP and GLP-1 receptor agonist. The licensed titration ladder steps every four weeks: 2.5, 5, 7.5, 10, 12.5 and 15 mg once weekly, with 2.5 mg treated as a starting dose rather than a maintenance one.
Note that the licensed product is a pre-filled pen at a fixed concentration. Reconstituting a vial yourself means you set the concentration, so the unit numbers below will not match anything printed on a pen.
Common vial and water combinations
| Vial | BAC water | Concentration | Draw | U-100 units | Doses/vial |
|---|---|---|---|---|---|
| 10 mg | 1 mL | 10 mg/mL | 0.5 mL | 50 units | 2 |
| 10 mg | 2 mL | 5 mg/mL | 1 mL | 100 units | 2 |
| 10 mg | 3 mL | 3.33 mg/mL | 1.5 mL | 150 units | 2 |
| 30 mg | 1 mL | 30 mg/mL | 0.167 mL | 16.7 units | 6 |
| 30 mg | 2 mL | 15 mg/mL | 0.333 mL | 33.3 units | 6 |
| 30 mg | 3 mL | 10 mg/mL | 0.5 mL | 50 units | 6 |
| 60 mg | 1 mL | 60 mg/mL | 0.083 mL | 8.3 units | 12 |
| 60 mg | 2 mL | 30 mg/mL | 0.167 mL | 16.7 units | 12 |
| 60 mg | 3 mL | 20 mg/mL | 0.25 mL | 25 units | 12 |
All rows above assume a 5 mg dose and a standard U-100 insulin syringe, where 100 units = 1 mL.
How long it stays in you
The half-life of Tirzepatide is about 5 days. That is the time for the amount in your blood to halve, so after one half-life you are at 50 percent of the peak, after two you are at 25 percent, and after four you are at roughly 6 percent. This is why a weekly compound still has meaningful levels present when the next dose lands, and why levels build over the first several weeks before they settle.
Calculators by compound
Common questions
- How many units is 5 mg of tirzepatide?
- In a 30 mg vial with 3 mL of water the concentration is 10 mg/mL, so 5 mg is 0.5 mL, which is 50 units on a U-100 syringe. In a 10 mg vial with 2 mL it is 5 mg/mL, so 5 mg is 100 units, a full syringe.
- How much water for a 30 mg tirzepatide vial?
- 3 mL is common and gives 10 mg/mL, so the whole 2.5 to 15 mg ladder lands between 25 and 150 units. Doses above 10 mg will exceed a 1 mL syringe at that concentration, so use less water if you are running high.
- How many doses in a 60 mg vial?
- Divide 60 by your weekly dose. At 5 mg that is 12 doses, or 84 days. At 15 mg it is 4 doses.
- Is compounded tirzepatide the same as the licensed product?
- No. Concentration, excipients and quality control differ. Anything you reconstitute yourself is at a concentration you chose, so unit counts from a pen do not transfer.